Studies towards enzymatic kinetic resolutions of 1,3-diol peptidomimetics obtained via the Ugi reaction
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چکیده
منابع مشابه
Sulfur-Switch Ugi Reaction for Macrocyclic Disulfide-Bridged Peptidomimetics
A general strategy is introduced for the efficient synthetic access of disulfide linked artificial macrocycles via a Ugi four-component reaction (U4CR) followed by oxidative cyclization. The double-mercapto input is proposed for use in the Ugi reaction, thereby yielding all six topologically possible combinations. The protocol is convergent and short and enables the production of novel disulfid...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2013
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.p008.122